Monkeypox

[Peter Cobbold]

WHO has raised the alert level on monkeypox today.

The pox viruses are enveloped and are known to be susceptible to  cathelicidin/LL37: https://www.jimmunol.org/content/172/3/1763#sec-10

As we have seen in the coronavirus thread, LL37 expression is promoted by vitamin D.

Here we go again..............

Peter

[john.r.davies]

Oh, for goodness sake, Peter. 

  Monkey Pox is spread by close personal contact, in  fact at present, ALL the UK cases are in "men who sleep with men".   That's where HIV took off and that soon spread to heterosexual transmission, but unless our colleagues here are promiscuous (and why not?) they are not at risk!

If you are, then follow the guidance from the NHS: Monkeypox - NHS (www.nhs.uk) and contact your GP, so that you may have the vaccine.   But you may have to wait -  smallpox vaccine works but as there has been NO  smallpox in the world since 1979 , there isn't a big stock of it.     But we can make it, or a specific MPV  vaccine, and now that WHO has designated the Pox as a Public Health Hazard, that will happen.

Dietary supplements are unnecessary and ineffective, compared to the vaccine.

  John

 

[RogerH]

2 hours ago, john.r.davies said:

Oh, for goodness sake, Peter. 

  Monkey Pox is spread by close personal contact, in  fact at present, ALL the UK cases are in "men who sleep with men".   That's where HIV took off and that soon spread to heterosexual transmission, but unless our colleagues here are promiscuous (and why not?) they are not at risk!

If you are, then follow the guidance from the NHS: Monkeypox - NHS (www.nhs.uk) and contact your GP, so that you may have the vaccine.   But you may have to wait -  smallpox vaccine works but as there has been NO  smallpox in the world since 1979 , there isn't a big stock of it.     But we can make it, or a specific MPV  vaccine, and now that WHO has designated the Pox as a Public Health Hazard, that will happen.

Dietary supplements are unnecessary and ineffective, compared to the vaccine.

  John

 

I don't think they are sleeping.!!!

 

Roger

[boxofbits]

[Peter Cobbold]

4 hours ago, john.r.davies said:

Oh, for goodness sake, Peter. 

  Monkey Pox is spread by close personal contact, in  fact at present, ALL the UK cases are in "men who sleep with men".   That's where HIV took off and that soon spread to heterosexual transmission, but unless our colleagues here are promiscuous (and why not?) they are not at risk!

If you are, then follow the guidance from the NHS: Monkeypox - NHS (www.nhs.uk) and contact your GP, so that you may have the vaccine.   But you may have to wait -  smallpox vaccine works but as there has been NO  smallpox in the world since 1979 , there isn't a big stock of it.     But we can make it, or a specific MPV  vaccine, and now that WHO has designated the Pox as a Public Health Hazard, that will happen.

Dietary supplements are unnecessary and ineffective, compared to the vaccine.

  John

 

 It is curious isnt it that sharp on the heels of an (unfinished) pandemic coronavirus, another enveloped virus alerts WHO. As a scientist I see a common mechanism in play: poor innate immunity, caused by sub-physiological D3 levels. Only a tiny fraction of the global population has physiological 25(OH)D.

Or do we blame the spread of these viruses on lack of vaccination? -when we know immunity has been evolving for >200million years, and vaccines are invented.

Peter

[PodOne]

I'm afraid the bigger the population the more these once rare viruses and the opportunity for novel and common variants to have the opportunity to spread or worse jump species. The mind boggles on the last one!

Andy